More of an expression I guess, but one that sets my teeth on edge. Two close friends of mine use it frequently and it's all I can do to not say anything about it. And, they use it so often with me that obviously it must be an ingrained part of their vocabulary.
"anywho", it comes out of their mouths almost like "anywhooo" as opposed to anyway or any how. GRRRRRRRRRRRRRRRRR!!!!
Lagatta, it's usually used at the end of a discussion or description of a particular situation summoning up with this "owl" like cutesy expression that one would expect from a teenager, young adult or Meg Ryan. And, because it's often times meant as a segue to a response, it's that much more difficult to respond to.